Article
Influence of toll-like receptor 4, CD14, tumor necrosis factor, and interleukine-10 gene polymorphisms on clinical outcome in Japanese critically ill patients.
The Journal of surgical research - 1 Dec 2005
Nakada Taka-Aki, Hirasawa Hiroyuki, Oda Shigeto, Shiga Hidetoshi, Matsuda Ken-Ichi, Nakamura Masataka, Watanabe Eizo, Abe Ryuzo, Hatano Masahiko, Tokuhisa Takeshi
Abstract excerpt
The innate recognition of microbial components and subsequent activation of cytokine network are important in the pathophysiology of sepsis. Recently, functional gene polymorphisms in molecules associated with these responses were demonstrated. On the other hand, it has been claimed that there ar...
Topics
- APACHE
- Adult
- Aged
- Critical Illness
- Female
- Genotype
- Humans
- Interleukin-10
- Japan
- Lipopolysaccharide Receptors
- Lymphotoxin-alpha