Article
H9c2 and HL-1 cells demonstrate distinct features of energy metabolism, mitochondrial function and sensitivity to hypoxia-reoxygenation.
Biochimica et biophysica acta - 1 Feb 2015
Kuznetsov Andrey V, Javadov Sabzali, Sickinger Stephan, Frotschnig Sandra, Grimm Michael
Abstract excerpt
Dysfunction of cardiac energy metabolism plays a critical role in many cardiac diseases, including heart failure, myocardial infarction and ischemia-reperfusion injury and organ transplantation. The characteristics of these diseases can be elucidated in vivo, though animal-free in vitro experiments, with primary adult or neonatal cardiomyocytes, the rat ventricular H9c2 cell line or the mouse atrial HL-1 cells,...
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