Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic modifications of gene promoter DNA in the liver of adult female mice masculinized by testosterone.

The Journal of steroid biochemistry and molecular biology - 1 Jan 2015

Dkhil Mohamed A, Al-Quraishy Saleh, Abdel-Baki Abdel-Azeem, Ghanjati Foued, Arauzo-Bravo Marcos J, Delic Denis, Wunderlich Frank

Abstract excerpt

Testosterone (T) is known to masculinize the female phenotype of the liver, evidenced as up- and down-regulated expressions of male- and female-predominant genes, respectively, involved in hepatic metabolism. This study is aimed at identifying epigenetic modifications of promoters of these differ...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CpG Islands
Share to DNA Methylation
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoprecipitation

Share to Mice, Inbred C57BL

Share to Oligonucleotide Array Sequence Analysis

Share to Testosterone

Source

Identifiers

PMID: 25448745
DOI: 10.1016/j.jsbmb.2014.11.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25448745-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic modifications of gene promoter DNA in the liver of adult female mice masculinized by testosterone.PMID 25448745Read ↗

Feminization of Male Mouse Liver by Persistent Growth Hormone Stimulation: Activation of Sex-Biased Transcriptional Networks and Dynamic Changes in Chromatin StatesSemantic proximity Read ↗

Transcriptional Profiling of Human Liver Identifies Sex-Biased Genes Associated with Polygenic Dyslipidemia and Coronary Artery DiseaseSemantic proximity Read ↗

Liver-specific hepatocyte nuclear factor-4alpha deficiency: greater impact on gene expression in male than in female mouse liver.Semantic proximity Read ↗

HDI-STARR-seq Identifies Functional GH-regulated Sex-Biased Hepatocyte Enhancers Linked to Liver Metabolism and DiseaseSemantic proximity Read ↗

Sumoylated PPARα mediates sex-specific gene repression and protects the liver from estrogen-induced toxicity in miceSemantic proximity Read ↗

Pharmacological activation of constitutive androstane receptor induces female-specific modulation of hepatic metabolismSemantic proximity Read ↗

Harnessing natural variation to identify cis regulators of sex-biased gene expression in a multi-strain mouse liver model.Semantic proximity Read ↗

Liver-specific ablation of Krüppel-associated box-associated protein 1 in mice leads to male-predominant hepatosteatosis and development of liver adenoma.Semantic proximity Read ↗

Harnessing natural variation to identify <i>cis</i> regulators of sex-biased gene expression in a multi-strain mouse liver modelSemantic proximity Read ↗

Sex Differences in the Expression of Drug-Metabolizing and Transporter Genes in Human LiverSemantic proximity Read ↗

Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2Semantic proximity Read ↗

Sex-specific KDM6A-HNF4A-CREBH network controls lipoprotein cholesterol metabolism and atherosclerosis via epigenetic reprograming of hepatocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.