Article
The gustin (CA6) gene polymorphism, rs2274333 (A/G), is associated with fungiform papilla density, whereas PROP bitterness is mostly due to TAS2R38 in an ethnically-mixed population.
Physiology & behavior - 1 Jan 2015
Barbarossa Iole Tomassini, Melis Melania, Mattes Mitchell Z, Calò Carla, Muroni Patrizia, Crnjar Roberto, Tepper Beverly J
Abstract excerpt
PROP responsiveness is associated with TAS2R38 haplotypes and fungiform papilla density. Recently, we showed that a polymorphism in the gene coding for the salivary trophic factor, gustin (CA6), affects PROP sensitivity by acting on cell growth and fungiform papillae maintenance, in a genetically...
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