Gene Methylation Affects Salivary Levels of the Taste Buds' Trophic Factor, Gustin Protein.

doi:10.3390/nu16091304

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Article

Gene Methylation Affects Salivary Levels of the Taste Buds' Trophic Factor, Gustin Protein.

Nutrients - 26 Apr 2024

Melis Melania, Loi Eleonora, Mastinu Mariano, Naciri Lala Chaimae, Zavattari Patrizia, Barbarossa Iole Tomassini

Abstract excerpt

The salivary protein, Gustin/carbonic anhydrase VI, has been described as a trophic factor responsible for the growth of taste buds. We found, in a genetically homogeneous population, that the polymorphism rs2274333 (A/G) of the Gustin gene is crucial for the full functionality of the protein and is associated with taste sensitivity. However, other studies have failed to find this evidence. Here, we verified if...

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PMID: 38732551
DOI: 10.3390/nu16091304
PMCID: PMC11085126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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