Article
GITR promoter polymorphism contributes to risk of coal workers' pneumoconiosis: a case-control study from China.
Immunology letters - 1 Dec 2014
Wu Baiqun, Ji Xiaoming, Han Ruhui, Han Lei, Wang Ting, Yang Jingjin, Zhu Baoli, Ni Chunhui
Abstract excerpt
BACKGROUND: Glucocorticoid-induced tumor necrosis factor (TNF) receptor-related protein (GITR) mainly affects the functions of effector T cells and regulatory T cells thus it may influence various diseases. Coal workers' pneumoconiosis (CWP) is a serious occupational disease worldwide. In the present study, we examined the association between the functional polymorphisms in GITR and risk of CWP in a Chinese...
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