Article
Associations of IL-4, IL-4R, and IL-13 gene polymorphisms in coal workers' pneumoconiosis in China: a case-control study.
PloS one - 1 Jan 2011
Wang Meilin, Wang Shasha, Song Zhifang, Ji Xiaomin, Zhang Zhengdong, Zhou Jianwei, Ni Chunhui
Abstract excerpt
BACKGROUND: The IL-4, IL-4 receptor (IL4R), and IL-13 genes are crucial immune factors and may influence the course of various diseases. In the present study, we investigated the association between the potential functional polymorphisms in IL-4, IL-4R, and IL-13 and coal workers' pneumoconiosis (CWP) risk in a Chinese population. METHODS: Six polymorphisms (C-590T in IL-4, Ile50Val, Ser478Pro, and Gln551Arg in...
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