BDNF polymorphism associates with decline in set shifting in Parkinson's disease.

doi:10.1016/j.neurobiolaging.2014.08.023

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Article

BDNF polymorphism associates with decline in set shifting in Parkinson's disease.

Neurobiology of aging - 1 Mar 2015

van der Kolk Nicolien M, Speelman Arlene D, van Nimwegen Marlies, Kessels Roy P C, IntHout Joanna, Hakobjan Marina, Munneke Marten, Bloem Bastiaan R, van de Warrenburg Bart P

Abstract excerpt

Parkinson's disease (PD) is a neurodegenerative disorder caused by nigrostriatal dopaminergic degeneration. Brain-derived neurotrophic factor (BDNF) is a key protein in brain plasticity and is particularly important for survival of dopaminergic neurons. The Val66Met polymorphism of BDNF (rs6265) has been associated with functional differences (mainly cognitive) between healthy adults and also with differences in...

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PMID: 25444596
DOI: 10.1016/j.neurobiolaging.2014.08.023

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BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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BDNF polymorphism associates with decline in set shifting in Parkinson's disease.PMID 25444596Read ↗

Val66Met BDNF polymorphism is associated with Parkinson's disease cognitive impairmentSemantic proximity Read ↗

BDNF G196A (Val66Met) polymorphism associated with cognitive impairment in Parkinson's disease.Semantic proximity Read ↗

The BDNF Val66Met polymorphism has a gender specific influence on planning ability in Parkinson's disease.Semantic proximity Read ↗

More than an “inverted-U”? An exploratory study of the association between the catechol-o-methyltransferase gene polymorphism and executive functions in Parkinson’s diseaseSemantic proximity Read ↗

Association of BDNF Val66MET Polymorphism With Parkinson's Disease and Depression and Anxiety Symptoms.Semantic proximity Read ↗

BDNF rs6265 Variant Alters Outcomes with Levodopa in Early-Stage Parkinson's Disease.Semantic proximity Read ↗

Association between the Val66Met (rs6265) polymorphism of the brain-derived neurotrophic factor (BDNF) gene, BDNF protein level in the blood and the risk of developing early‑onset Parkinson's disease.Semantic proximity Read ↗

No association between brain-derived neurotrophic factor G196A polymorphism and clinical features of Parkinson's disease.Semantic proximity Read ↗

BDNF val66met influences time to onset of levodopa induced dyskinesia in Parkinson's disease.Semantic proximity Read ↗

Effect of BDNF Val66Met polymorphism on normal variability of executive functions.Semantic proximity Read ↗

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