Article
BDNF polymorphism associates with decline in set shifting in Parkinson's disease.
Neurobiology of aging - 1 Mar 2015
van der Kolk Nicolien M, Speelman Arlene D, van Nimwegen Marlies, Kessels Roy P C, IntHout Joanna, Hakobjan Marina, Munneke Marten, Bloem Bastiaan R, van de Warrenburg Bart P
Abstract excerpt
Parkinson's disease (PD) is a neurodegenerative disorder caused by nigrostriatal dopaminergic degeneration. Brain-derived neurotrophic factor (BDNF) is a key protein in brain plasticity and is particularly important for survival of dopaminergic neurons. The Val66Met polymorphism of BDNF (rs6265)...
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