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Article

The anti-cancer actions of O6-methylguanine-DNA-methyltransferase in relation to colon polyps.

Pharmacological reports : PR - 1 Dec 2014

Kycler Witold, Korski Konstanty, Loziński Cezary, Teresiak-Mańczak Anna, Przybyła Anna, Mackiewicz Andrzej, Cybulski Zefiryn, Lamperska Katarzyna

Abstract excerpt

BACKGROUND: Genetic variability in DNA repair genes may contribute to differences in DNA repair capacity and susceptibility to colon polyps and cancer. In this study, we examined the role of MGMT polymorphisms in colon polyps formation. METHODS: PCR-SSCP analysis was performed included 254 patients with colon polyps and 330 controls. RESULTS: The homozygous F84F genotype was significantly more prevalent in study...

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PMID: 25443735
DOI: 10.1016/j.pharep.2014.06.019

Genes

MGMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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