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Article

Intraindividual somatic variations in MTHFR gene polymorphisms in relation to colon cancer.

Pharmacogenomics - 1 Feb 2014

Rai Padmalatha S, Pai Ganesh C, Alvares Jose F, Bellampalli Ravishankara, Gopinath Puthiya M, Satyamoorthy Kapaettu

Abstract excerpt

AIM: MTHFR mediates the one carbon metabolism pathway. Two common genetic variants, C677T and A1298C, of MTHFR are associated with number of human diseases, including cancer, as well as being involved in the modulation of therapy outcome to antifolate drugs. To understand the distribution pattern...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24533714
DOI: 10.2217/pgs.14.4

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24533714-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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