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Article

ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study.

The Lancet. Neurology - 1 Oct 2007

van Es Michael A, Van Vught Paul W, Blauw Hylke M, Franke Lude, Saris Christiaan G, Andersen Peter M, Van Den Bosch Ludo, de Jong Sonja W, van 't Slot Ruben, Birve Anna, Lemmens Robin, de Jong Vianney, Baas Frank, Schelhaas Helenius J, Sleegers Kristel, Van Broeckhoven Christine, Wokke John H J, Wijmenga Cisca, Robberecht Wim, Veldink Jan H, Ophoff Roel A, van den Berg Leonard H

Abstract excerpt

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a devastating disease characterised by progressive degeneration of motor neurons in the brain and spinal cord. ALS is thought to be multifactorial, with both environmental and genetic causes. Our aim was to identify genetic variants that predispo...

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Source

Identifiers

PMID: 17827064
DOI: 10.1016/S1474-4422(07)70222-3

Genes

ITPR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17827064-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study.PMID 17827064Read ↗

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