Article
A case study of comprehensive association analysis and risk prediction of amyotrophic lateral sclerosis in a Chinese population.
Molecular biology reports - 3 Jul 2026
Xie Xueying, Jiao Xiaoqing, Yang Ke, Zhang Qianqian
Abstract excerpt
BACKGROUND: Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease with significant genetic heterogeneity. While large-scale studies have characterized its genetic architecture in European populations, the genetic basis of ALS in the Chinese population remains under-explored. METHODS AND RESULTS: To address this gap, we conducted a comprehensive genetic analysis on a cohort of 40 Chinese...
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