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Article

A genome-wide association study of sporadic ALS in a homogenous Irish population.

Human molecular genetics - 1 Mar 2008

Cronin Simon, Berger Stephen, Ding Jinhui, Schymick Jennifer C, Washecka Nicole, Hernandez Dena G, Greenway Matthew J, Bradley Daniel G, Traynor Bryan J, Hardiman Orla

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive limb or bulbar weakness. Efforts to elucidate the disease-associated loci have to date produced conflicting results. One strategy to improve power in genome-wide studies is to genotype a genetically homogenous population. Such a population exhibits extended linkage disequilibrium (LD) and lower allelic...

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Source

Identifiers

PMID: 18057069
DOI: 10.1093/hmg/ddm361

Genes

DPP6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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