Article
Genetic alterations in renal cell carcinoma with rhabdoid differentiation.
Human pathology - 1 Jan 2015
Perrino Carmen M, Hucthagowder Vishwanathan, Evenson Michael, Kulkarni Shashikant, Humphrey Peter A
Abstract excerpt
Renal cell carcinoma with rhabdoid differentiation (RCC-R) in adult patients is an aggressive variant of renal cancer with no known specific genetic alterations. The aim of this study was to characterize genome-wide genetic aberrations in RCC-R via utilization of high-density single-nucleotide polymorphism (SNP) arrays. We identified 20 cases of RCC-R, which displayed both clear cell renal cell carcinoma and...
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