Article
Spontaneous chromosomal instability in breast cancer families.
Cancer genetics and cytogenetics - 1 Apr 2000
Roy S K, Trivedi A H, Bakshi S R, Patel R K, Shukla P H, Patel S J, Bhatavdekar J M, Patel D D, Shah P M
Abstract excerpt
Spontaneous chromosomal instability has been correlated with cancer predisposition. In the present study, the phenomenon has been evaluated using two cytogenetic markers, namely, frequency of spontaneous sister chromatid exchanges (SCE) and spontaneous chromosomal aberrations (CA) in peripheral blood lymphocytes of hereditary breast cancer (HBC) patients (n = 11) and healthy blood relatives (HBR, n = 36). A...
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