Article
Association of sister chromatid exchange frequencies in patients with ankylosing spondylitis with and without HLA-B27.
Annals of the rheumatic diseases - 1 Aug 2003
Ikbal M, Ezirmik N, Tos T, Pirim I
Abstract excerpt
BACKGROUND: The analysis of sister chromatid exchange (SCE) is a cytogenetic technique used to show DNA damage due to an exchange of DNA fragments between sister chromatids. OBJECTIVE: To determine whether HLA-B27 positive patients with ankylosing spondylitis (AS) were associated with higher SCE frequencies than patients without B27. METHODS: Lymphocytes from 38 patients with AS (15 women, 23 men) and 34 control...
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