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Article

Estrogen receptor status could modulate the genomic pattern in familial and sporadic breast cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2007

Melchor Lorenzo, Honrado Emiliano, Huang Jia, Alvarez Sara, Naylor Tara L, García María J, Osorio Ana, Blesa David, Stratton Michael R, Weber Barbara L, Cigudosa Juan C, Rahman Nazneen, Nathanson Katherine L, Benítez Javier

Abstract excerpt

PURPOSE: Familial breast cancer represents 5% to 10% of all breast tumors. Mutations in the two known major breast cancer susceptibility genes, BRCA1 and BRCA2, account for a minority of familial breast cancer, whereas families without mutations in these genes (BRCAX group) account for 70% of fam...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18094411
DOI: 10.1158/1078-0432.CCR-07-0711

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18094411-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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