Article
Identifying structural variation in haploid microbial genomes from short-read resequencing data using breseq.
BMC genomics - 29 Nov 2014
Barrick Jeffrey E, Colburn Geoffrey, Deatherage Daniel E, Traverse Charles C, Strand Matthew D, Borges Jordan J, Knoester David B, Reba Aaron, Meyer Austin G
Abstract excerpt
BACKGROUND: Mutations that alter chromosomal structure play critical roles in evolution and disease, including in the origin of new lifestyles and pathogenic traits in microbes. Large-scale rearrangements in genomes are often mediated by recombination events involving new or existing copies of mobile genetic elements, recently duplicated genes, or other repetitive sequences. Most current software programs for...
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