Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GenHtr: a tool for comparative assessment of genetic heterogeneity in microbial genomes generated by massive short-read sequencing.

BMC bioinformatics - 12 Oct 2010

Yu Gongxin

Abstract excerpt

BACKGROUND: Microevolution is the study of short-term changes of alleles within a population and their effects on the phenotype of organisms. The result of the below-species-level evolution is heterogeneity, where populations consist of subpopulations with a large number of structural variations. Heterogeneity analysis is thus essential to our understanding of how selective and neutral forces shape bacterial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Genetic Heterogeneity
Share to Genome, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Share to Software

Share to Staphylococcus aureus

Source

Open in PubMed Open full text

Identifiers

PMID: 20939910
DOI: 10.1186/1471-2105-11-508
PMCID: PMC2967562

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GenHtr: a tool for comparative assessment of genetic heterogeneity in microbial genomes generated by massive short-read sequencing.PMID 20939910Read ↗

Genotyping of evolving prokaryotic populationsSemantic proximity Read ↗

Gnom(Cmp): a quantitative approach for comparative analysis of closely related genomes of bacterial pathogens.Semantic proximity Read ↗

Analyzing rare mutations in metagenomes assembled using long and accurate reads.Semantic proximity Read ↗

GeneScanner: profiling genetic variation across bacterial populations.Semantic proximity Read ↗

Average nucleotide identity-based Staphylococcus aureus strain grouping allows identification of strain-specific genes in the pangenomeSemantic proximity Read ↗

Giant transposons promote strain heterogeneity in a major fungal pathogen.Semantic proximity Read ↗

Identifying structural variation in haploid microbial genomes from short-read resequencing data using breseq.Semantic proximity Read ↗

Giant transposons promote strain heterogeneity in a major fungal pathogenSemantic proximity Read ↗

Whole-genome sequencing for high-resolution investigation of methicillin-resistant Staphylococcus aureus epidemiology and genome plasticity.Semantic proximity Read ↗

Pathogen microevolution in high resolution.Semantic proximity Read ↗

Assessment of Oxford Nanopore whole genome sequencing for large-scale genomic characterisation of <i>Staphylococcus aureus</i> bacteraemia isolatesSemantic proximity Read ↗

Short read sequence typing (SRST): multi-locus sequence types from short readsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.