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Article

CED-3 caspase acts with miRNAs to regulate non-apoptotic gene expression dynamics for robust development in C. elegans.

eLife - 30 Dec 2014

Weaver Benjamin P, Zabinsky Rebecca, Weaver Yi M, Lee Eui Seung, Xue Ding, Han Min

Abstract excerpt

Genetic redundancy and pleiotropism have limited the discovery of functions associated with miRNAs and other regulatory mechanisms. To overcome this, we performed an enhancer screen for developmental defects caused by compromising both global miRISC function and individual genes in Caenorhabditis elegans. Among 126 interactors with miRNAs, we surprisingly found the CED-3 caspase that has only been well studied...

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Identifiers

PMID: 25432023
DOI: 10.7554/eLife.04265
PMCID: PMC4279084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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