Article

Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival

2023-02-13

Abstract excerpt

<title>Abstract</title> <p>Breast cancer (BC) patients with a germline <italic>CHEK2</italic> c.1100delC variant have an increased risk of contralateral BC (CBC) and worse BC-specific survival (BCSS) compared to non-carriers. We aimed to assess the associations of <italic>CHEK2</italic> c.1100delC, radiotherapy, and systemic treatment with CBC risk and BCSS. Analyses were based on 82,701 women diagnosed with inva...

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Literature Corpus work: aa488a89-fa73-5eae-b8a6-343ae197b604
DOI: 10.21203/rs.3.rs-2569372/v1

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