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Article

A new type of toxin A-negative, toxin B-positive Clostridium difficile strain lacking a complete tcdA gene.

Journal of clinical microbiology - 1 Feb 2015

Janezic Sandra, Marín Mercedes, Martín Adoración, Rupnik Maja

Abstract excerpt

Toxins A and B are the main virulence factors of Clostridium difficile and are the targets for molecular diagnostic tests. Here, we describe a new toxin A-negative, toxin B-positive, binary toxin CDT (Clostridium difficile transferase)-negative (A(-) B(+) CDT(-)) toxinotype (XXXII) characterized by a variant type of pathogenicity locus (PaLoc) without tcdA and with atypical organization of the PaLoc integration site.

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Identifiers

PMID: 25428159
DOI: 10.1128/JCM.02211-14
PMCID: PMC4298534

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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