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Phosphatases of Î±-synuclein, LRRK2, and tau: important players in the phosphorylation-dependent pathology of Parkinsonism

7 Nov 2014

Abstract excerpt

An important challenge in the field of Parkinson's disease (PD) is to develop disease modifying therapies capable of stalling or even halting disease progression. Coupled to this challenge is the need to identify disease biomarkers, in order to identify pre-symptomatic hallmarks of disease and monitor disease progression. The answer to these challenges lies in the elucidation of the molecular causes underlying...

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PMID: 25426138
DOI: 10.3389/fgene.2014.00382

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