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Article

LRRK2: a common pathway for parkinsonism, pathogenesis and prevention?

Trends in molecular medicine - 1 Feb 2006

Taylor Julie P, Mata Ignacio F, Farrer Matt J

Abstract excerpt

The presence of alpha-synuclein Lewy body pathology is used to distinguish Parkinson's disease from parkinsonism, for which a broader spectrum of neuropathologies, including tau-immunopositive neurofibrillary tangles and ubiquitin inclusions, might accompany nigral neuronal loss. These neuropathologies define the endpoint of many neurodegenerative disorders but might be symptomatic rather than causative....

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Identifiers

PMID: 16406842
DOI: 10.1016/j.molmed.2005.12.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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