Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Therapeutic treatments of mtDNA diseases at the earliest stages of human development.

Mitochondrion - 1 Sept 2011

Chiaratti Marcos Roberto, Meirelles Flávio Vieira, Wells Dagan, Poulton Joanna

Abstract excerpt

More than 150 pathogenic mitochondrial DNA (mtDNA) mutations associated with a range of illnesses have been described in humans. These mutations are carried by one in 400 people and their inheritance is exclusively maternal. Currently there is no method to prevent mtDNA diseases, which highlights the need for strategies to predict their transmission. Here we outline the scientific background and unique...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytoplasm
Share to DNA, Mitochondrial
Share to Heredity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitochondrial Diseases

Share to Mutation

Share to Nuclear Transfer Techniques

Share to Preimplantation Diagnosis

Share to Selection, Genetic

Source

Identifiers

PMID: 21147275
DOI: 10.1016/j.mito.2010.11.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Therapeutic treatments of mtDNA diseases at the earliest stages of human development.PMID 21147275Read ↗

Genetic and reproductive strategies to prevent mitochondrial diseasesSemantic proximity Read ↗

A Two-Genome Portrayal of Mitochondrial Disorders: A Review with Clinical Presentations.Semantic proximity Read ↗

Clinical Approaches for Mitochondrial Diseases.Semantic proximity Read ↗

Lessons from mitochondrial DNA mutations.Semantic proximity Read ↗

Mitochondrial DNA disorders: from pathogenic variants to preventing transmission.Semantic proximity Read ↗

Mitochondrial DNA medicine.Semantic proximity Read ↗

Mitochondrial replacement: from basic research to assisted reproductive technology portfolio tool-technicalities and possible risks.Semantic proximity Read ↗

Epidemiology and treatment of mitochondrial disorders.Semantic proximity Read ↗

Clinical and ethical implications of mitochondrial gene transfer.Semantic proximity Read ↗

The inheritance of pathogenic mitochondrial DNA mutations.Semantic proximity Read ↗

Mitochondrial DNA mutations in the pathogenesis of human disease.Semantic proximity Read ↗

Pathogenic Mitochondria DNA Mutations: Current Detection Tools and Interventions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.