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Blood-based DNA Methylation Biomarkers for Early Detection of Colorectal Cancer

1 Jan 2018

Abstract excerpt

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Early detection of CRC can significantly reduce this mortality rate. Unfortunately, recommended screening modalities, including colonoscopy, are hampered by poor patient acceptance, low sensitivity and high cost. Recent studies have demonstrated that colorectal oncogenesis is a multistep event resulting from the accumulation of a...

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PMID: 30034186
DOI: 10.4172/jpb.1000477

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