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Article

gone early, a novel germline factor, ensures the proper size of the stem cell precursor pool in the Drosophila ovary.

PloS one - 1 Jan 2014

Matsuoka Shinya, Gupta Swati, Suzuki Emiko, Hiromi Yasushi, Asaoka Miho

Abstract excerpt

In order to sustain lifelong production of gametes, many animals have evolved a stem cell-based gametogenic program. In the Drosophila ovary, germline stem cells (GSCs) arise from a pool of primordial germ cells (PGCs) that remain undifferentiated even after gametogenesis has initiated. The decision of PGCs to differentiate or remain undifferentiated is regulated by somatic stromal cells: specifically, epidermal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25420147
DOI: 10.1371/journal.pone.0113423
PMCID: PMC4242634

Genes

EGFR
PGC
EGF
GSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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