Article

Zebrafish Foxl2l suppresses stemness of germline progenitors and directs feminization

2024-04-04

Abstract excerpt

Zebrafish is an important organism for genetic studies, but its germ cell types and the mechanism of sex differentiation remain elusive. Here, we conducted a single-cell transcriptomic profiling and charted a developmental trajectory going from germline stem cells, through early, committed, and late progenitors, to pre-meiotic and meiotic cells. A transcription factor, Foxl2l, is expressed in the progenitors commi...

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Literature Corpus work: 8a4b6990-45ed-5421-b7f2-4f57e88b75c9
DOI: 10.1101/2024.04.03.587938

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