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Article

Lysyl hydroxylase 3 modifies lysine residues to facilitate oligomerization of mannan-binding lectin.

PloS one - 1 Jan 2014

Risteli Maija, Ruotsalainen Heli, Bergmann Ulrich, Venkatraman Girija Umakhanth, Wallis Russell, Myllylä Raili

Abstract excerpt

Lysyl hydroxylase 3 (LH3) is a multifunctional protein with lysyl hydroxylase, galactosyltransferase and glucosyltransferase activities. The LH3 has been shown to modify the lysine residues both in collagens and also in some collagenous proteins. In this study we show for the first time that LH3 is essential for catalyzing formation of the glucosylgalactosylhydroxylysines of mannan-binding lectin (MBL), the first...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 25419660
DOI: 10.1371/journal.pone.0113498
PMCID: PMC4242627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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