Article
Lysyl hydroxylase 3 is a multifunctional protein possessing collagen glucosyltransferase activity.
The Journal of biological chemistry - 17 Nov 2000
Heikkinen J, Risteli M, Wang C, Latvala J, Rossi M, Valtavaara M, Myllylä R
Abstract excerpt
Lysyl hydroxylase (EC ) and glucosyltransferase (EC ) are enzymes involved in post-translational modifications during collagen biosynthesis. We reveal in this paper that the protein produced by the cDNA for human lysyl hydroxylase isoform 3 (LH3) has both lysyl hydroxylase and glucosyltransferase (GGT) activities. The other known lysyl hydroxylase isoforms, LH1, LH2a, and LH2b, have no GGT activity. Furthermore,...
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