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Article

The activities of lysyl hydroxylase 3 (LH3) regulate the amount and oligomerization status of adiponectin.

PloS one - 1 Jan 2012

Ruotsalainen Heli, Risteli Maija, Wang Chunguang, Wang Yu, Karppinen Marjo, Bergmann Ulrich, Kvist Ari-Pekka, Pospiech Helmut, Herzig Karl-Heinz, Myllylä Raili

Abstract excerpt

Lysyl hydroxylase 3 (LH3) has lysyl hydroxylase, galactosyltransferase, and glucosyltransferase activities, which are sequentially required for the formation of glucosylgalactosyl hydroxylysines in collagens. Here we demonstrate for the first time that LH3 also modifies the lysine residues in the collagenous domain of adiponectin, which has important roles in glucose and lipid metabolism and inflammation....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23209641
DOI: 10.1371/journal.pone.0050045
PMCID: PMC3510199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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