Article
Relationship between HSP70-2 A+1267G Polymorphism and Cardiovascular Events of Chinese Peritoneal Dialysis Patients.
Nephron. Clinical practice - 1 Jan 2014
Poon Peter Yam-Kau, Szeto Cheuk-Chun, Kwan Bonnie Ching-Ha, Chow Kai-Ming, Li Philip Kam-Tao
Abstract excerpt
BACKGROUND: Heat shock proteins (HSPs) are expressed by cells in response to various environmental stresses. A single-nucleotide polymorphism A+1267G of the HSPA1B gene affects the expression of HSP70-2, with the A allele being protective against inflammatory conditions. We investigated the relation between the HSP A+1267G polymorphism and the clinical outcomes of Chinese peritoneal dialysis (PD) patients....
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