Article
Interactive association of heat shock protein 70 genes variants with natural longevity in Xinjiang Hetian Uygur ethnicity.
Translational research : the journal of laboratory and clinical medicine - 1 Nov 2009
Li Jinxin, Niu Wenquan, Qi Yue, Mayila Wufuer, Zhu Pengcheng, Muhuyati, Cheng Zuheng, Qiu Changchun
Abstract excerpt
Mounting evidence suggests that all organisms at the cellular level respond to stress by synthesizing heat shock proteins at the expense of other proteins, and the ability of human cells to respond to heat stress decreases with aging. We thus investigate the association of 3 variants (A1267G in HSPA1B, G190C in HSPA1A, and T2437C in HSPA1L) in the heat shock protein 70 (Hsp70) family with natural longevity in a...
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