Article
Association of heat shock protein70-2 (HSP70-2) gene polymorphism with coronary artery disease in an Iranian population.
Gene - 25 Oct 2014
Mardan-Nik Maryam, Pasdar Alireza, Jamialahmadi Khadijeh, Biabangard-Zak Atefeh, Mirhafez Seyed Reza, Ghalandari Marzieh, Tajfard Mohammad, Mohebati Mohsen, Esmaily Habibollah, Ferns Gordon A, Ghayour-Mobarhan Majid
Abstract excerpt
BACKGROUND: Coronary artery disease (CAD) is an inflammatory process and a major cause of mortality and morbidity. The (heat shock protein70-2) HSP70-2 gene is reported to be associated with coronary artery disease possibly by affecting the regulation of pro-inflammatory cytokines such as TNF-α. The association between CAD and the HSP70-2 gene +1267A>G polymorphism has been studied in some populations but there...
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