Article
Relationship between CRP polymorphism and cardiovascular events in Chinese peritoneal dialysis patients.
Clinical journal of the American Society of Nephrology : CJASN - 1 Feb 2012
Poon Peter Yam-Kau, Szeto Cheuk-Chun, Kwan Bonnie Ching-Ha, Chow Kai-Ming, Li Philip Kam-Tao
Abstract excerpt
BACKGROUND AND OBJECTIVES: The single-nucleotide polymorphism (SNP) -717A→G substitution, rs2794521, was found in the promoter of the C-reactive protein (CRP) gene. Functional studies showed that A allele promoter has higher transcriptional activity than the G allele. This study investigated the association between this SNP and the outcome of Chinese patients undergoing peritoneal dialysis (PD). DESIGN, SETTING,...
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