Article
Association of A1538G and C2437T single nucleotide polymorphisms in heat shock protein-70 genes with diabetic nephropathy among South Indian population.
Bioscience reports - 28 Apr 2017
Dhamodharan Umapathy, Ezhilarasi Krishnamoorthy, Ponjayanthi Balashanmugam, Sireesh Dornadula, Ramkumar Kunka Mohanram, Viswanathan Vijay
Abstract excerpt
Diabetic Nephropathy (DN) is the leading cause of end-stage renal disease, characterized by progressive albuminuria and conferring additional risk of cardiovascular disease (CVD) and mortality. The crucial role of heat-shock proteins (HSPs) on renal function in patients with DN has been well documented. The present study was aimed to understand the association of HSP-70 gene variants on the susceptibility of Type...
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