Article
Identification of a human mitochondrial RNA that promotes tropomyosin synthesis and myocardial differentiation.
In vitro cellular & developmental biology. Animal - 1 Mar 2015
Moses-Arms Ashley, Kochegarov Andrei, Arms Jedidiah, Burlbaw Shane, Lian Will, Meyer Jessica, Lemanski Larry F
Abstract excerpt
Heart disease is the number one killer in the USA, making cardiogenesis and its related pathways a relevant area of study for improving health and life expectancy. The Mexican salamander (axolotl), Ambystoma mexicanum, provides an excellent vertebrate animal model for studying myofibrillogenesis due to its naturally occurring cardiac nonfunction mutation. Homozygous recessive embryos do not develop normal hearts...
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