Article
In vivo characterization of human myofibrillar myopathy genes in zebrafish.
Biochemical and biophysical research communications - 29 May 2015
Bührdel John B, Hirth Sofia, Kessler Mirjam, Westphal Sören, Forster Monika, Manta Linda, Wiche Gerhard, Schoser Benedikt, Schessl Joachim, Schröder Rolf, Clemen Christoph S, Eichinger Ludwig, Fürst Dieter O, van der Ven Peter F M, Rottbauer Wolfgang, Just Steffen
Abstract excerpt
Myofibrillar myopathies (MFM) are progressive diseases of human heart and skeletal muscle with a severe impact on life quality and expectancy of affected patients. Although recently several disease genes for myofibrillar myopathies could be identified, today most genetic causes and particularly the associated mechanisms and signaling events that lead from the mutation to the disease phenotype are still mostly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.