Pri-Mir-34b/C and Tp-53 Polymorphisms are Associated With The Susceptibility of Papillary Thyroid Carcinoma: A Case-Control Study.

doi:10.1097/MD.0000000000001536

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Article

Pri-Mir-34b/C and Tp-53 Polymorphisms are Associated With The Susceptibility of Papillary Thyroid Carcinoma: A Case-Control Study.

Medicine - 1 Sept 2015

Chen Peng, Sun Ruifen, Pu Yan, Bai Peng, Yuan Fang, Liang Yundan, Zhou Bin, Wang Yanyun, Sun Yinghe, Zhu Jingqiang, Zhang Lin, Gao Linbo

Abstract excerpt

Tumor suppressor p53 directly regulated the abundance of the miR-34b/c. The interaction might contribute to certain cancer. We hypothesized that rs4938723 in the promoter region of pri-miR-34b/c and TP-53 Arg72Pro may be related to the risk of papillary thyroid carcinoma (PTC). A total of 784 patients with PTC and 1006 healthy controls were recruited to participate in this study. The variants were discriminated...

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PMID: 26402809
DOI: 10.1097/MD.0000000000001536
PMCID: PMC4635749

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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