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Article

Monocyte-platelet interaction induces a pro-inflammatory phenotype in circulating monocytes.

PloS one - 1 Jan 2011

Passacquale Gabriella, Vamadevan Padman, Pereira Luis, Hamid Colleen, Corrigall Valerie, Ferro Albert

Abstract excerpt

BACKGROUND: Activated platelets exert a pro-inflammatory action that can be largely ascribed to their ability to interact with leukocytes and modulate their activity. We hypothesized that platelet activation and consequent formation of monocyte-platelet aggregates (MPA) induces a pro-inflammatory phenotype in circulating monocytes. METHODOLOGY/PRINCIPAL FINDINGS: CD62P(+) platelets and MPA were measured, and...

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Identifiers

PMID: 22022418
DOI: 10.1371/journal.pone.0025595
PMCID: PMC3192052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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