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Article

The role of monocytes in thrombotic disorders

1 Jan 2009

Abstract excerpt

Although, the main physiological role of monocytes is attributed to innate immunity (that is, phagocytosis) and the development of tissue macrophages and dendritic cells, the pathophysiological role of these goes far behind these (simplistic) limits. Indeed, monocytes constitute a major source of blood tissue factor, a key element of the extrinsic coagulation cascade. Monocytes actively bind to platelets, thus...

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Share to Antiplatelet Therapy and Cardiovascular Diseases
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PMID: 19888530
DOI: 10.1160/th09-01-0023

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