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Article

Gene-environment interactions in determining differences in genetic susceptibility to cancer in subsites of the head and neck.

Environmental and molecular mutagenesis - 1 Apr 2015

Maurya Shailendra S, Katiyar Tridiv, Dhawan Ankur, Singh Sudhir, Jain Swatantra K, Pant Mohan C, Parmar Devendra

Abstract excerpt

Genetic differences in susceptibility to cancer in subsites of the head and neck were investigated in a case-control study involving 750 cases of cancers of the oral cavity, larynx, or pharynx, and an equal number of healthy controls. The prevalence of variant genotypes of cytochrome P450 (CYP) 1A1, 1B1, 2E1, or glutathione-S-transferase M1 (null) in cases suggests that polymorphisms in drug metabolizing enzymes...

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Identifiers

PMID: 25399842
DOI: 10.1002/em.21920

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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