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Article

Pharmacogenomic diversity of tamoxifen metabolites and estrogen receptor genes in Hispanics and non-Hispanic whites with breast cancer.

Breast cancer research and treatment - 1 Dec 2014

Rangel Leticia B A, Taraba Jodi L, Frei Christopher R, Smith Lon, Rodriguez Gladys, Kuhn John G

Abstract excerpt

Ethnic differences in patient genetics and breast cancer (BC) biology contribute to ethnic disparities in cancer presentation and patient outcome. We prospectively evaluated SNPs within phase I and phase II tamoxifen (TAM) metabolizing enzymes, and the estrogen receptor gene (ESR1), aiming to identify potential pharmacogenomic ethnicity patterns in an ER-positive BC cohort constituted of Hispanic and Non-Hispanic...

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Source

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Identifiers

PMID: 25395315
DOI: 10.1007/s10549-014-3191-4
PMCID: PMC4413900

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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