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Pharmacokinetics and Pharmacogenomics of Ribociclib in Black Patients with Metastatic Breast Cancer: The LEANORA study

2024-08-13

Abstract excerpt

<title>Abstract</title> <p>Underrepresented populations' participation in clinical trials remains limited, and the potential impact of genomic variants on drug metabolism remains elusive. This study aimed to assess the pharmacokinetics (PK) and pharmacogenomics (PGx) of ribociclib in self-identified Black women with hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2) advanced...

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Literature Corpus work
e95167cb-a773-5640-b71a-b0b19d1cce6c
DOI
10.21203/rs.3.rs-4656461/v1
Open publication

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Pharmacokinetics and Pharmacogenomics of Ribociclib in Black Patients with Metastatic Breast Cancer: The LEANORA studyDOI 10.21203/rs.3.rs-4656461/v1
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