Article
Genomics and pharmacogenomics of breast cancer: current knowledge and trends.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011
Ayoub Nehad, Lucas Courtney, Kaddoumi Amal
Abstract excerpt
The impact of genomics and pharmacogenomics in the current arena of clinical oncology is well-established. In breast cancer, mutations in the BRCA1 and BRCA2 genes have been well-characterized to carry a high risk of the disease during a woman's lifespan. However, these high risk genes contribute to only a small proportion of the familial cases of breast cancer. Hence, further efforts aimed to study the...
Topics
- Antineoplastic Agents
- Aromatase
- Breast Neoplasms
- Cytochrome P-450 CYP2D6
- Female
- Genes, BRCA1
- Genes, BRCA2
- Genetic Predisposition to Disease
- Genomics
- Humans
- Pharmacogenetics