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Article

Integrative genomic analyses of a novel cytokine, interleukin-34 and its potential role in cancer prediction.

International journal of molecular medicine - 1 Jan 2015

Wang Bo, Xu Wenming, Tan Miaolian, Xiao Yan, Yang Haiwei, Xia Tian-Song

Abstract excerpt

Interleukin-34 (IL-34) is a novel cytokine, which is composed of 222 amino acids and forms homodimers. It binds to the macrophage colony-stimulating factor (M-CSF) receptor and plays an important role in innate immunity and inflammatory processes. In the present study, we identified the completed IL-34 gene in 25 various mammalian genomes and found that IL-34 existed in all types of vertebrates, including fish,...

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Identifiers

PMID: 25395235
DOI: 10.3892/ijmm.2014.2001
PMCID: PMC4249750

Genes

FOXL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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