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Article

Integration of QTL and comprehensive analysis in the circulating inflammatory cytokines for pan-cancer.

BMC cancer - 13 Aug 2024

Lin Haishan, Cao Bangwei

Abstract excerpt

BACKGROUND: Chemokines and cytokines are components of the tumor microenvironment and also influence tumorigenesis and its composition. However, whether they genetically proxy tumorigenesis is unclear. For causal inferences, eQTL and pQTL were used to determine the role of chemokines and cytokines in pan-cancer. The impact on the tumor immune microenvironment was also explored. METHODS: This study leveraged...

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Cytokines
Genome-Wide Association Study
Neoplasms
Polymorphism, Single Nucleotide
Quantitative Trait Loci

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Microenvironment

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PMID: 39138392
DOI: 10.1186/s12885-024-12726-4
PMCID: PMC11323443

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