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MicroRNA-34 Family in Cancers: Role, Mechanism, and Therapeutic Potential

2023-08-10

Abstract excerpt

MicroRNA (miRNA) is small non-coding RNAs that play vital roles in post-transcriptional gene regulation by inhibiting mRNA translation or promoting mRNA degradation. Dysregulation of miRNA has been implicated in numerous human diseases, including cancers. The family members of miR-34 (miR-34s), composed of miR-34a, miR-34b, and miR-34c, have emerged as the most extensively studied tumor-suppressive miRNAs. In this...

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Literature Corpus work
8258e15e-bd02-5917-9b60-9b4c6d93209f
DOI
10.20944/preprints202308.0847.v1
Open publication

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