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Article

Integrative genomic analysis of interleukin-36RN and its prognostic value in cancer.

Molecular medicine reports - 1 Feb 2016

Lv Zhilei, Fan Jinshuo, Zhang Xiuxiu, Huang Qi, Han Jieli, Wu Feng, Hu Guorong, Guo Mengfei, Jin Yang

Abstract excerpt

Interleukin (IL)-36RN, previously known as IL1-F5 and IL-1δ, shares a 360-kb region of chromosome 2q13 with members of IL-1 systems. IL-36RN encodes an anti-inflammatory cytokine, IL-36 receptor antagonist (IL-36Ra). In spite of IL-36Ra showing the highest homology to IL-1 receptor (IL-1R) antagonist, it differs from the latter in aspects including its binding to IL-lRrp2 but not to IL-1R1. IL-36RN is mainly...

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PMID: 26676204
DOI: 10.3892/mmr.2015.4667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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