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Article

The molecular pathogenesis of primary mediastinal large B-cell lymphoma

24 Jun 2011

Abstract excerpt

Primary mediastinal large B-cell lymphoma (PMBCL) is a recognized non-Hodgkin lymphoma entity with unique pathologic, clinical, and molecular characteristics distinct from those of other diffuse large B-cell lymphomas. Immunohistochemical characterization and molecular studies strongly suggest that PMBCL is of germinal center or postgerminal center origin. Pivotal gene expression profiling work defined major...

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PMID: 21700770
DOI: 10.1182/blood-2011-05-326538

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